Phosphine

Phosphine

SCHEMBL27645652

P.c1cc(Sc2cc[nH]n2)n[nH]1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154871 0.80 EHMT2 (0.31)
SCHEMBL3480583 0.79 HPGD (0.41)
SCHEMBL27534134 0.79 EHMT2 (0.48)
SCHEMBL369555 0.79
SCHEMBL28467547 0.77
SCHEMBL27365650 0.77
SCHEMBL27369237 0.77 HAO1 (0.53)
SCHEMBL27529897 0.76 NOTUM (0.47)
SCHEMBL3203798 0.76
SCHEMBL8838233 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1774268-A Bifunctional tridentate pyrazolyl containing ligands for rhenium and technetium tricarbonyl complexes MALLINCKRODT INC (US) 2006-05-17 CN claimed
CN-101928327-A Bifunctional tridentate pyrazolyl containing ligands for re and tc tricarbonyl complexes MALLINCKRODT INC 2010-12-29 CN disclosed
CN-1774268-A Bifunctional tridentate pyrazolyl containing ligands for rhenium and technetium tricarbonyl complexes MALLINCKRODT INC (US) 2006-05-17 CN disclosed