Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19361446 | 0.78 | PTGDR2 (0.63) | PTGDR2AKR1B1PTGDRCYP2C9PTGIR | |
| SCHEMBL1787716 | 0.76 | PTGDR2 (0.64) | PTGDR2AKR1B1PTGDRCYP2C9 | |
| SCHEMBL1759180 | 0.76 | PTGDR2 (0.60) | PTGDR2AKR1B1PTGDRCYP2C9PTGIR | |
| SCHEMBL1785965 | 0.74 | PTGDR2 (0.56) | PTGDR2AKR1B1PTGDRCYP2C9 | |
| SCHEMBL1785003 | 0.74 | PTGDR2 (0.56) | PTGDR2AKR1B1PTGDRCYP2C9 | |
| SCHEMBL1788163 | 0.74 | PTGDR2 (0.66) | PTGDR2AKR1B1PTGDRCYP2C9 | |
| SCHEMBL1466409 | 0.74 | PTGDR2 (0.56) | PTGDR2PTGDRCYP2C9PTGIR | |
| SCHEMBL24180014 | 0.73 | PTGDR2 (0.53) | PTGDR2AKR1B1PTGDRCYP2C9PTGIR | |
| SCHEMBL1786162 | 0.73 | PTGDR2 (0.62) | PTGDR2PTGDRCYP2C9PTGIR | |
| SCHEMBL5435403 | 0.73 | PTGDR2 (0.67) | PTGDR2AKR1B1PTGDRCYP2C9PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1867547-A | Compounds having crth2 antagonist activity | OXAGEN LTD (GB) | 2006-11-22 | — | — | CN | disclosed |