Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845314 | 0.87 | CA12 (0.53) | KMT2AMAPTMEN1LMNATTR | |
| SCHEMBL4055672 | 0.87 | CA12 (0.53) | KMT2AMAPTMEN1LMNATTR | |
| SCHEMBL4055668 | 0.87 | CA12 (0.53) | KMT2AMAPTMEN1LMNATTR | |
| SCHEMBL14672568 | 0.86 | ESR1 (0.48) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL2561337 | 0.84 | F3 (0.64) | KMT2AMAPTMEN1LMNACYP3A4 | |
| SCHEMBL19244302 | 0.84 | ESR1 (0.51) | KMT2AMAPTMEN1LMNAESR1 | |
| SCHEMBL19244300 | 0.84 | ESR1 (0.51) | KMT2AMAPTMEN1LMNAESR1 | |
| SCHEMBL2561341 | 0.84 | F3 (0.64) | KMT2AMAPTMEN1LMNACYP3A4 | |
| SCHEMBL13845250 | 0.84 | ELANE (0.53) | KMT2AMAPTMEN1LMNAKDM4E | |
| SCHEMBL13845249 | 0.84 | ELANE (0.53) | KMT2AMAPTMEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1764648-A | Hydroxamic acid derivatives as inhibitors of Histone Deacetylase (HDAC) | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-04-26 | — | — | CN | disclosed |