Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460658 | 0.85 | GAA (0.62) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL27851348 | 0.76 | GAA (0.47) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL999259 | 0.76 | GAA (0.47) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL13698473 | 0.74 | MEN1 (0.53) | MEN1KMT2AGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL20755413 | 0.72 | GAA (0.54) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL377688 | 0.72 | NOTUM (0.53) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL5460651 | 0.72 | NOTUM (0.53) | MEN1KMT2ATSHRNPSR1NOTUM | |
| SCHEMBL14566099 | 0.72 | NOTUM (0.57) | GAAMEN1USP2KMT2ATSHR | |
| SCHEMBL24843808 | 0.71 | HSD17B10 (0.55) | MEN1KMT2ATSHRNPSR1GLA | |
| SCHEMBL21448022 | 0.71 | NPY5R (0.51) | TSHRGLANOTUMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910166-A | Heteroaryl ureas and their use as glucokinase activators | NOVO NORDISK AS (DK) | 2007-02-07 | — | — | CN | disclosed |