Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646262 | 0.91 | FFAR3 (0.33) | LMNABLMSMN1; SMN2FFAR3MAPK1 | |
| SCHEMBL5899717 | 0.71 | FFAR3 (0.42) | ALDH1A1LMNAUSP2CYP1A2TSHR | |
| SCHEMBL5899602 | 0.64 | USP2 (0.44) | ALDH1A1LMNACPB2USP2CYP1A2 | |
| SCHEMBL5899767 | 0.64 | USP2 (0.44) | ALDH1A1LMNACPB2USP2CYP1A2 | |
| SCHEMBL5899580 | 0.64 | USP2 (0.44) | ALDH1A1LMNACPB2USP2CYP1A2 | |
| SCHEMBL5899695 | 0.63 | GRM2 (0.34) | FFAR3 | |
| Hydrochloric Acid SCHEMBL5644052 | 0.63 | USP2 (0.42) | ALDH1A1LMNACPB2USP2CYP1A2 | |
| SCHEMBL28849710 | 0.62 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL5899689 | 0.62 | USP2 (0.36) | ALDH1A1LMNAUSP2CYP1A2TSHR | |
| SCHEMBL5643708 | 0.62 | USP2 (0.41) | ALDH1A1LMNACPB2USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1764634-A | Cyclopropyl beta-amino acid derivatives | WARNER LAMBERT CO (US) | 2006-04-26 | — | — | CN | claimed |
| CN-1764634-A | Cyclopropyl beta-amino acid derivatives | WARNER LAMBERT CO (US) | 2006-04-26 | — | — | CN | disclosed |