Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646420 | 1.00 | TSHR (0.35) | TSHRHPGDACE2S1PR5TP53 | |
| SCHEMBL27626043 | 1.00 | TSHR (0.35) | TSHRHPGDACE2S1PR5TP53 | |
| SCHEMBL27646389 | 0.99 | TSHR (0.35) | TSHRHPGDACE2S1PR5TP53 | |
| SCHEMBL28758544 | 0.95 | TSHR (0.38) | TSHRHPGDS1PR5GPR84FFAR1 | |
| SCHEMBL27646346 | 0.91 | TSHR (0.33) | TSHR | |
| SCHEMBL27646431 | 0.90 | TSHR (0.40) | TSHRHPGDS1PR5GPR84FFAR1 | |
| SCHEMBL28758549 | 0.90 | TSHR (0.40) | TSHRHPGDS1PR5GPR84FFAR1 | |
| SCHEMBL27626010 | 0.87 | TSHR (0.34) | TSHRHPGD | |
| SCHEMBL28758552 | 0.84 | TSHR (0.39) | TSHRHPGDS1PR5GPR84FFAR1 | |
| SCHEMBL27646585 | 0.84 | EPHX2 (0.31) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410646-A | Torque limiter | JTEKT CORP (JP) | 2009-04-15 | — | — | CN | disclosed |
| CN-1784203-A | Cosmetic composition containing cyclohexane polycarboxylic acid derivative | BASF AG (DE) | 2006-06-07 | — | — | CN | disclosed |