Ethylene Glycol

Ethylene Glycol

SCHEMBL27646409

CC(C)CCCCCCCCCOC(=O)C1CCC(C(=O)O)CC1.OCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.37
RARB P10826 1/20 0.33
S1PR5 Q9H228 2/20 0.33
S1PR1 P21453 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
ESR1 P03372 1/20 0.32
GBA2 Q9HCG7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL27646505 1.00 PPARG (0.37) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL27646450 0.96 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL1297545 0.96 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL1297528 0.96 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL1297176 0.96 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL1297665 0.96 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
Ethylene Glycol SCHEMBL1297827 0.94 PPARG (0.39) PPARGS1PR5S1PR1PPM1BPTPN1
SCHEMBL1296424 0.94 PPARG (0.40) PPARGRARBS1PR5S1PR1PPM1B
SCHEMBL1296697 0.90 PPARG (0.41) PPARGS1PR5S1PR1PPM1BPTPN1
SCHEMBL1297269 0.89 PPARG (0.37) PPARGRARBESR1GBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101410646-A Torque limiter JTEKT CORP (JP) 2009-04-15 CN disclosed
CN-1784203-A Cosmetic composition containing cyclohexane polycarboxylic acid derivative BASF AG (DE) 2006-06-07 CN disclosed