Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 15/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874642 | 0.88 | AOC3 (0.61) | AOC3MAOBHDAC1HDAC6ALDH1A1 | |
| SCHEMBL27626575 | 0.87 | AOC3 (0.48) | AOC3MAOBHDAC1HDAC6 | |
| SCHEMBL3406120 | 0.81 | AOC3 (0.61) | AOC3MAOB | |
| SCHEMBL27646805 | 0.79 | MAPK1 (0.46) | ALDH1A1 | |
| SCHEMBL27646817 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1 | |
| SCHEMBL3934166 | 0.77 | AOC3 (0.85) | AOC3MAOB | |
| SCHEMBL4873462 | 0.76 | AOC3 (0.55) | AOC3MAOBHDAC1HDAC6 | |
| SCHEMBL13679476 | 0.75 | AOC3 (0.58) | AOC3MAOB | |
| Hydrochloric Acid SCHEMBL4876215 | 0.74 | AOC3 (0.57) | AOC3MAOB | |
| SCHEMBL4876641 | 0.74 | AOC3 (0.73) | AOC3MAOBHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491361-C | Thiazole derivatives and their use as VAP-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1761655-A | Thiazole derivatives and their use as VAP-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-04-19 | — | — | CN | disclosed |