Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 18/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934867 | 0.85 | AOC3 (0.73) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL970829 | 0.85 | AOC3 (0.76) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL4864956 | 0.85 | AOC3 (0.76) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL3939548 | 0.84 | AOC3 (0.74) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL971466 | 0.83 | AOC3 (0.78) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL972537 | 0.83 | AOC3 (0.78) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL975119 | 0.83 | AOC3 (0.78) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL3935659 | 0.82 | AOC3 (0.85) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL973099 | 0.82 | AOC3 (0.76) | AOC3MAOBKMT2ASMN1; SMN2 | |
| SCHEMBL972612 | 0.82 | AOC3 (0.76) | AOC3MAOBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491361-C | Thiazole derivatives and their use as VAP-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1761655-A | Thiazole derivatives and their use as VAP-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-04-19 | — | — | CN | disclosed |