Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.69 |
| ▸ | BCR | P11274 | 8/20 | 0.69 |
| ▸ | LYN | P07948 | 6/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.66 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.66 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
| ▸ | RET | P07949 | 1/20 | 0.66 |
| ▸ | ARAF | P10398 | 1/20 | 0.66 |
| ▸ | BRAF | P15056 | 1/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.66 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.66 |
| ▸ | CSK | P41240 | 1/20 | 0.66 |
| ▸ | ABL2 | P42684 | 1/20 | 0.66 |
| ▸ | FRK | P42685 | 1/20 | 0.66 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.66 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.66 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.66 |
| ▸ | EPHA5 | P54756 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651406 | 1.00 | ABL1 (0.69) | ABL1BCRLYNPDGFRBRIPK2 | |
| Hydrochloric Acid SCHEMBL27651417 | 0.99 | ABL1 (0.68) | ABL1BCRLYNPDGFRBRIPK2 | |
| Hydrochloric Acid SCHEMBL27671583 | 0.99 | ABL1 (0.68) | ABL1BCRLYNPDGFRBRIPK2 | |
| SCHEMBL27651408 | 0.92 | ABL1 (0.67) | ABL1BCRLYNPDGFRBRIPK2 | |
| SCHEMBL27651407 | 0.92 | ABL1 (0.67) | ABL1BCRLYNPDGFRBRIPK2 | |
| Hydrochloric Acid SCHEMBL28762321 | 0.92 | ABL1 (0.66) | ABL1BCRLYNPDGFRBRIPK2 | |
| Hydrochloric Acid SCHEMBL28762325 | 0.92 | ABL1 (0.66) | ABL1BCRLYNPDGFRBRIPK2 | |
| SCHEMBL27651403 | 0.91 | ABL1 (0.67) | ABL1BCRLYNPDGFRBRIPK2 | |
| SCHEMBL27671586 | 0.91 | ABL1 (0.63) | ABL1BCRLYNPDGFRBRIPK2 | |
| SCHEMBL27651391 | 0.89 | ABL1 (0.70) | ABL1BCRLYNPDGFRBRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100526298-C | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2009-08-12 | — | — | CN | claimed |
| CN-1898208-A | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | CN | claimed |
| CN-100526298-C | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
| CN-101456841-A | Amide derivative and medicine | NIPPON SHINYAKU CO LTD (JP) | 2009-06-17 | — | — | CN | disclosed |
| CN-1898208-A | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | CN | disclosed |