Melagatran

Melagatran

SCHEMBL27652

N=C(N)c1ccc(CNC(=O)[C@@H]2CCN2C(=O)[C@H](NCC(=O)O)C2CCCCC2)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2 P00734 20/20 0.64
F10 P00742 1/20 0.57
PROC P04070 1/20 0.57
F7 P08709 1/20 0.57
MASP2 O00187 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Melagatran SCHEMBL23840802 1.00 F2 (0.64) F2F10PROCF7MASP2
Melagatran SCHEMBL8083301 1.00 F2 (0.64) F2F10PROCF7MASP2
Melagatran SCHEMBL20567754 1.00 F2 (0.64) F2F10PROCF7MASP2
Melagatran SCHEMBL5706395 0.99 F2 (0.63) F2F10PROCF7MASP2
Melagatran SCHEMBL3209070 0.99 F2 (0.63) F2F10PROCF7MASP2
Melagatran SCHEMBL27557537 0.99 F2 (0.63) F2F10PROCF7MASP2
Melagatran SCHEMBL29160734 0.99 F2 (0.63) F2F10PROCF7MASP2
SCHEMBL23793366 0.99 F2 (0.62) F2F10PROCF7MASP2
SCHEMBL23840808 0.95 F2 (0.64) F2F10PROCF7
SCHEMBL23840772 0.95 F2 (0.64) F2F10PROCF7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6142 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075463-A Pharmaceutical composition containing melagatran besylate and preparation method thereof 2026-05-26 CN claimed
CN-122075429-A 20Mg core-pressed or core-shell type biphasic release tablet containing mezloballin or pharmaceutically acceptable salt thereof and preparation method thereof 2026-05-26 CN claimed
CN-122005480-A Meloxepin besylate tablet and preparation method thereof 山东鲁抗医药股份有限公司 2026-05-12 CN claimed
US-12605371-B2 Combination therapy for cancer THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-21 US claimed
US-12521258-B2 Anticoagulant compounds and methods and devices for their use ELIXIR MEDICAL CORPORATION (US) 2026-01-13 US claimed
WO-2025262269-A1 MONITORING OF REVERSAL AGENTS FOR ANTICOAGULANTS ENZYRE B.V. (NL) 2025-12-26 WO claimed
EP-4658806-A1 DISPOSABLE CARTRIDGE FOR CLASSIFICATION OF ANTICOAGULANT AND METHOD OF USE Haemonetics Corporation (US) 2025-12-10 EP claimed
US-20250347706-A1 DISPOSABLE CARTRIDGE FOR CLASSIFICATION OF ANTICOAGULANT AND METHOD OF USE HAEMONETICS CORP (US) 2025-11-13 US claimed
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 EP claimed
CN-120131636-A Twin medicine and composition and application thereof 江苏海洋大学 2025-06-13 CN claimed
EP-0942960-A1 PROMOTION OF REGENERATION OF ORGANIZED TISSUES Hansson, Hans-Arne (SE) 1999-09-22 EP claimed
CN-1219965-A Promoting regeneration of organotypic tissue HANS ARNE HANSSON (SE) 1999-06-16 CN claimed
WO-1999027913-A1 POLYETHYLENE GLYCOL MATRIX PELLETS FOR GREASY, OILY OR STICKY DRUG SUBSTANCES ASTRAZENECA AB (SE) 1999-06-10 WO claimed
WO-1999027912-A1 POROUS HYDROXYAPATITE PARTICLES AS CARRIERS FOR DRUG SUBSTANCES ASTRAZENECA AB (SE) 1999-06-10 WO claimed
CN-1213309-A Control of healing process HANSSON HANS ARNE (SE) 1999-04-07 CN claimed
EP-0874634-A1 CONTROL OF HEALING PROCESS Hansson, Hans-Arne (SE) 1998-11-04 EP claimed
WO-1998016252-A1 NEW PHARMACEUTICAL PARENTERAL FORMULATION OF A THROMBIN INHIBITOR ASTRA AKTIEBOLAG (SE) 1998-04-23 WO claimed
WO-1997039770-A1 NEW PHARMACEUTICAL FORMULATION OF A THROMBIN INHIBITOR FOR PARENTERAL USE ASTRA AKTIEBOLAG (SE) 1997-10-30 WO claimed
WO-1997037002-A1 PROMOTION OF REGENERATION OF ORGANIZED TISSUES HANSSON HANS ARNE (SE) 1997-10-09 WO claimed
WO-1997025994-A1 CONTROL OF HEALING PROCESS HANSSON HANS ARNE (SE) 1997-07-24 WO claimed