Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651061 | 0.83 | GCK (0.68) | GCK | |
| SCHEMBL2651070 | 0.82 | GCK (0.55) | GCK | |
| SCHEMBL13255127 | 0.80 | GCK (0.65) | GCK | |
| SCHEMBL3613770 | 0.80 | GCK (0.65) | GCK | |
| SCHEMBL3605805 | 0.77 | GCK (0.67) | GCK | |
| SCHEMBL12742907 | 0.77 | GCK (0.56) | GCKSMN1; SMN2KMT2AHTTRAB9A | |
| SCHEMBL644849 | 0.76 | GCK (0.73) | GCKSMN1; SMN2 | |
| SCHEMBL1107697 | 0.75 | GCK (0.57) | GCKSMN1; SMN2 | |
| SCHEMBL1107731 | 0.74 | AKR1C3 (0.68) | GCKNPC1RAB9A | |
| SCHEMBL643258 | 0.74 | GCK (0.48) | GCKSMN1; SMN2KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777589-A | Heteroarylcarbamoylbenzene derivatives | BANYU PHARMA CO LTD (JP) | 2006-05-24 | — | — | CN | disclosed |