Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652473 | 0.88 | SMN1; SMN2 (0.61) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27652503 | 0.87 | SMN1; SMN2 (0.48) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10590678 | 0.85 | SMN1; SMN2 (0.61) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27652478 | 0.84 | HDAC6 (0.56) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27672732 | 0.84 | TP53 (0.54) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2242771 | 0.79 | NPC1 (0.72) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL17199120 | 0.79 | NPC1 (0.81) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL27358173 | 0.79 | ESR1 (0.53) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2248809 | 0.79 | ESR1 (0.81) | ESR1ESR2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL30727500 | 0.78 | SMN1; SMN2 (0.65) | ESR1ESR2SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482717-C | Polybenzole kind aryl ether monomer, copolymer and its synthesis method | JINHUAN LI (CN) | 2009-04-29 | — | — | CN | disclosed |
| CN-1869102-A | Polybenzole kind aryl ether monomer, copolymer and its synthesis method | LI JINHUAN (CN) | 2006-11-29 | — | — | CN | disclosed |