SCHEMBL27653149

SCHEMBL27653149

Nc1cccc2c1c1c(-c3ccccc3O)cccc1n2CCO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
NR1I2 O75469 1/20 0.36
SMARCA2 P51531 1/20 0.36
SMARCA4 P51532 1/20 0.36
PBRM1 Q86U86 1/20 0.36
TSHR P16473 4/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 3/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 3/20 0.35
ALOX15 P16050 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 1/20 0.35
NPY1R P25929 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
NPY2R P49146 1/20 0.35
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887963 0.86 TLR8 (0.38) TSHRALDH1A1MAPTALOX15HTT
SCHEMBL3885265 0.84 TSHR (0.41) TSHRALDH1A1HPGDKDM4EMAPT
SCHEMBL3877435 0.77 MEN1 (0.45) TSHRALDH1A1KDM4EMAPTMEN1
SCHEMBL3881084 0.76 HTR2A (0.41) TSHRALDH1A1HPGDMAPTALOX15
SCHEMBL3873857 0.72 MEN1 (0.46) TSHRALDH1A1HPGDKDM4EMAPT
SCHEMBL3874408 0.68 MAPT (0.48) TSHRALDH1A1HPGDKDM4EMAPT
SCHEMBL3877422 0.68 MAPT (0.45) TSHRALDH1A1HPGDKDM4EMAPT
SCHEMBL3887845 0.66 WEE1 (0.38) TSHRKDM4EMAPTKMT2ALMNA
SCHEMBL3872751 0.66 WEE1 (0.38) TSHRKDM4EMAPTKMT2ALMNA
SCHEMBL3885459 0.66 MAPT (0.53) TSHRALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1937994-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-03-28 CN disclosed