Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653231 | 0.75 | DCAF1 (0.46) | ALDH1A1RAB9A | |
| SCHEMBL22897288 | 0.72 | CAPN1 (0.54) | — | |
| SCHEMBL20028370 | 0.72 | CAPN1 (0.54) | — | |
| SCHEMBL20148796 | 0.71 | AKT2 (0.47) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2109313 | 0.68 | EPHX1 (0.68) | EPHX1PPARGPPARACPA1ALDH1A1 | |
| SCHEMBL1516139 | 0.67 | EPHX1 (1.00) | EPHX1ALDH1A1ALPIPKMPTGS1 | |
| SCHEMBL28107950 | 0.67 | EPHX1 (0.77) | EPHX1MEN1KMT2APPARGPPARA | |
| SCHEMBL14678497 | 0.67 | EPHX1 (0.62) | EPHX1MEN1KMT2AHDAC8PPARG | |
| SCHEMBL13615358 | 0.67 | CHEK1 (0.46) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8620330 | 0.66 | EPHX1 (0.96) | EPHX1MEN1KMT2AALDH1A1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1802373-A | Pyrazoloisoquinoline derivatives as kinase inhibitors | AVENTIS PHARMA INC (US) | 2006-07-12 | — | — | CN | disclosed |