Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 19/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1125167 | 0.85 | NR1H2 (0.56) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL995354 | 0.83 | NR1H2 (0.58) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27765040 | 0.80 | NR1H2 (0.55) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL4264766 | 0.78 | NR1H2 (0.54) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124136 | 0.78 | NR1H2 (0.54) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1126131 | 0.77 | NR1H2 (0.71) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL35403 | 0.75 | NR1H2 (0.75) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124869 | 0.75 | NR1H2 (0.83) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1125411 | 0.74 | NR1H2 (0.62) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1126148 | 0.73 | NR1H2 (0.66) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |