Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241043 | 1.00 | MEN1 (0.54) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1242841 | 0.92 | MEN1 (0.58) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1243864 | 0.91 | MEN1 (0.53) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL27656155 | 0.91 | MEN1 (0.53) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL262069 | 0.84 | MEN1 (0.59) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1243435 | 0.83 | MEN1 (0.52) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1242761 | 0.83 | MEN1 (0.52) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL262257 | 0.83 | KDM4E (0.58) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1243443 | 0.82 | MEN1 (0.49) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL1242810 | 0.82 | MEN1 (0.51) | MEN1KMT2AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | claimed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | claimed |
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |