Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635209 | 0.93 | KDM4E (0.52) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL262257 | 0.92 | KDM4E (0.58) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL27635219 | 0.91 | KDM4E (0.56) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL31371946 | 0.90 | MEN1 (0.56) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL17387391 | 0.90 | MEN1 (0.56) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL1243820 | 0.87 | KMT2A (0.54) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL263654 | 0.84 | MEN1 (0.59) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL262995 | 0.82 | MEN1 (0.59) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL4103702 | 0.82 | MEN1 (0.53) | MEN1GAAKMT2AKDM4EALDH1A1 | |
| SCHEMBL6305154 | 0.81 | KDM4E (0.61) | MEN1GAAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |