Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.68 |
| ▸ | PPARA | Q07869 | 15/20 | 0.68 |
| ▸ | PPARD | Q03181 | 14/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764905 | 0.90 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL3522785 | 0.89 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL3532303 | 0.86 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL3527488 | 0.82 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL3525916 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL3525884 | 0.79 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL3520435 | 0.79 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL3527649 | 0.79 | PPARG (0.84) | PPARGPPARAPPARD | |
| SCHEMBL3523872 | 0.79 | PPARG (0.81) | PPARGPPARAPPARD | |
| SCHEMBL3522767 | 0.79 | PPARG (0.93) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919869-B1 | INDOLE DERIVATIVES AS PPAR ACTIVATORS | FOURNIER LAB SA (FR) | 2010-04-14 | — | — | EP | claimed |