Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515539 | 0.98 | POLB (0.41) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27802819 | 0.85 | POLB (0.42) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27802820 | 0.84 | MAPT (0.42) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27824900 | 0.78 | MAPT (0.42) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27908005 | 0.78 | CYP19A1 (0.40) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28849510 | 0.78 | POLB (0.40) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL28203981 | 0.78 | PARP1 (0.42) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27516905 | 0.78 | MAPT (0.43) | POLBKMT2AALDH1A1MAPTPDK1 | |
| SCHEMBL28476637 | 0.77 | TYR (0.41) | POLBKMT2AKDM4ECTDSP1TDP1 | |
| SCHEMBL27539515 | 0.77 | GRIN2D (0.38) | POLBKMT2AKDM4ECTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1944398-A | New benzoyl amide compounds and its preparing method and medicine use | INST OF MEDICINES CHINESE ACAD (CN) | 2007-04-11 | — | — | CN | disclosed |