SCHEMBL276573

SCHEMBL276573

NC(Cc1ccc(O)c(Br)c1Br)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.54
USP2 O75604 3/20 0.54
HIF1A Q16665 3/20 0.54
ALOX15 P16050 3/20 0.54
HSD17B10 Q99714 3/20 0.54
LMNA P02545 3/20 0.54
MAPT P10636 3/20 0.54
BLM P54132 3/20 0.54
PMP22 Q01453 3/20 0.54
KMT2A Q03164 3/20 0.54
RECQL P46063 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
PKM P14618 2/20 0.54
MEN1 O00255 2/20 0.54
CYP3A4 P08684 2/20 0.54
NFKB1 P19838 2/20 0.54
ALDH1A1 P00352 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
RGS12 O14924 1/20 0.54
CYP2C9 P11712 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5320585 1.00 KDM4E (0.54) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL5284385 0.88 KDM4E (0.53) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL6339538 0.85 KDM4E (0.50) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL5280931 0.79 KDM4E (0.64) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL29216329 0.79 KDM4E (0.58) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL454801 0.79 KDM4E (0.58) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL3513801 0.76 KDM4E (0.59) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL5324040 0.76 KDM4E (0.54) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL5320318 0.76 KDM4E (0.54) KDM4EUSP2HIF1AALOX15HSD17B10
SCHEMBL5324035 0.76 KDM4E (0.54) KDM4EUSP2HIF1AALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574138-B Dibromotyrosine-iridium complex and preparation method and application thereof 广东医科大学 2024-01-26 CN claimed
CN-116574138-A Dibromotyrosine-iridium complex and preparation method and application thereof 广东医科大学 2023-08-11 CN claimed
CN-109988312-B Polyamide acid ester, preparation method, negative polyimide composition and application 深圳先进技术研究院 2023-04-11 CN claimed
CN-105143245-B Anti-scaling material 耶路撒冷希伯来大学伊森姆研究发展有限公司 2021-02-05 CN claimed
CN-107523219-B Chemical Mechanical Polishing (CMP) of cobalt-containing substrates 弗萨姆材料美国有限责任公司 2020-12-29 CN claimed
US-10745589-B2 Chemical mechanical polishing (CMP) of cobalt-containing substrate VERSUM MATERIALS US, LLC (US) 2020-08-18 US claimed
EP-3257910-B1 CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION, METHOD AND SYSTEM FOR COBALT-CONTAINING SUBSTRATE VERSUM MAT US LLC (US) 2019-03-27 EP claimed
US-20170362466-A1 Chemical Mechanical Polishing (CMP) of Cobalt-Containing substrate VERSUM MATERIALS US, LLC (US) 2017-12-21 US claimed
EP-3257910-A1 CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION, METHOD AND SYSTEM FOR COBALT-CONTAINING SUBSTRATE Versum Materials US, LLC (US) 2017-12-20 EP claimed
CN-105873944-A Pro-angiogenic peptides and peptide conjugates 耶路撒冷希伯来大学伊森姆研究发展有限公司 2016-08-17 CN claimed
US-20040048739-A1 Catalyst comprising soluble polymer and polymino acid STYLACATS LIMITED (GB) 2004-03-11 US claimed
US-20030207324-A1 IMMUNOTHERAPY BY MODULATION OF ANTIGEN PRESENTATION HUMPHREYS ROBERT E 2003-11-06 US claimed
EP-1289974-A1 CATALYST COMPRISING SOLUBLE POLYMER AND POLYAMINO ACID Stylacats Ltd (GB) 2003-03-12 EP claimed
US-20020048775-A1 Diagnostic methods for asthma NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-04-25 US claimed
WO-2001094327-A1 CATALYST COMPRISING SOLUBLE POLYMER AND POLYAMINO ACID STYLACATS LIMITED (GB) 2001-12-13 WO claimed
US-6306576-B1 ANALYZING SAMPLE FOR 3-BROMOTYROSINE AND/OR 3,5-DIBROMOTYROSINE; ELEVATED LEVELS INDICATE DISEASE ASSOCIATED WITH ACTIVATED EOSINOPHILS CLEVELAND CLINIC FOUNDATION 2001-10-23 US claimed
US-5919639-A INCUBATING MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II EXPRESSING ANTIGEN PRESENTING CELL WITH MAMMALIAN INVARIANT CHAIN PEPTIDE OF 4-16 AMINO ACIDS, A MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II RESTRICTED ANTIGENIC PEPTIDE, AND A T CELL UNIVERSITY OF MASSACHUSETTS (US) 1999-07-06 US claimed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US claimed
WO-1997049430-A1 IMMUNOTHERAPY BY MODULATION OF ANTIGEN PRESENTATION ANTIGEN EXPRESS, INC. (US) 1997-12-31 WO claimed
EP-0769003-A1 AMINO ACID-DERIVED DIAMINOPROPANOLS Pharmeco Laboratories, Inc. (US) 1997-04-23 EP claimed