Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.62 |
| ▸ | ARG1 | P05089 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637418 | 0.98 | TLR8 (0.60) | TLR8ARG1HRH3P2RX7SIGMAR1 | |
| SCHEMBL27658198 | 0.89 | TLR8 (0.51) | TLR8ARG1HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL823462 | 0.88 | TLR8 (0.50) | TLR8ARG1HRH3SIGMAR1L3MBTL1 | |
| SCHEMBL28043028 | 0.78 | TLR8 (0.70) | TLR8ARG1KMT2A | |
| SCHEMBL27637305 | 0.78 | TLR8 (0.70) | TLR8ARG1KMT2A | |
| SCHEMBL5464719 | 0.77 | TLR8 (1.00) | TLR8ARG1KMT2ATLR7 | |
| SCHEMBL27637354 | 0.77 | TLR8 (0.68) | TLR8ARG1KMT2A | |
| SCHEMBL2060316 | 0.76 | TLR8 (0.49) | TLR8ARG1HRH3SIGMAR1 | |
| SCHEMBL6767282 | 0.76 | TLR8 (0.67) | TLR8ARG1HRH3KMT2A | |
| SCHEMBL27658200 | 0.76 | TLR8 (0.67) | TLR8ARG1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1858039-A | Synthetic method for 1-amino-3 (azacyclo alkyl)-2, 4-imidazole diketone | UNIV CHINA PHARMACY (CN) | 2006-11-08 | — | — | CN | disclosed |