Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 17/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697728 | 1.00 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL4696578 | 0.87 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL56685 | 0.86 | NTRK1 (0.63) | NTRK1JAK2JAK3 | |
| SCHEMBL56686 | 0.86 | NTRK1 (0.63) | NTRK1JAK2JAK3 | |
| SCHEMBL2634555 | 0.85 | NTRK1 (0.60) | NTRK1JAK2JAK3 | |
| SCHEMBL4696834 | 0.85 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL57982 | 0.85 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL27658432 | 0.85 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL57981 | 0.85 | NTRK1 (0.59) | NTRK1JAK2JAK3 | |
| SCHEMBL4086126 | 0.85 | NTRK1 (0.55) | NTRK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968933-A | Pyrazole derivatives useful for the treatment of cancer | ASTRAZENECA AB (SE) | 2007-05-23 | — | — | CN | disclosed |