Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517366 | 0.98 | PRSS1 (0.65) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| Hydrochloric Acid SCHEMBL9183990 | 0.96 | PRSS1 (0.63) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| Bromide SCHEMBL11186851 | 0.96 | PRSS1 (0.63) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| Hydrochloric Acid SCHEMBL11187297 | 0.96 | PRSS1 (0.63) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1450488 | 0.94 | PRSS1 (0.59) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL27920690 | 0.93 | PRSS1 (0.58) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| Hydrochloric Acid SCHEMBL320656 | 0.93 | PRSS1 (0.58) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL43233 | 0.90 | PRSS1 (0.67) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL1603335 | 0.88 | PRSS1 (0.56) | PRSS1PRSS2PRSS3KMT2AEGFR | |
| SCHEMBL25297232 | 0.88 | PRSS1 (0.70) | PRSS1PRSS2PRSS3KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103243129-A | Method for preparing beta-amino acid | SUNCHEM SHANGHAI CO LTD | 2013-08-14 | — | — | CN | disclosed |
| CN-1928102-B | Resolution method of beta-amino acid | ASTATECH CHENGDU PHARMACEUTIACL CO LTD | 2011-08-10 | — | — | CN | disclosed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | disclosed |
| CN-1928102-A | Resolution method of beta-amino acid | ASTATECH CHENGDU PHARMACEUTIAC (CN) | 2007-03-14 | — | — | CN | disclosed |