Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27870386 | 1.00 | TSHR (0.35) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL27865363 | 0.98 | TSHR (0.32) | TSHRGGPS1 | |
| SCHEMBL27481524 | 0.86 | TSHR (0.39) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL27368342 | 0.79 | TSHR (0.33) | TSHRTHRBGGPS1 | |
| SCHEMBL28542877 | 0.77 | TSHR (0.37) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL11409740 | 0.74 | TSHR (0.44) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL8560947 | 0.74 | TSHR (0.44) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL9543818 | 0.74 | TSHR (0.44) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL11416194 | 0.74 | TSHR (0.44) | TSHRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL15929348 | 0.74 | TSHR (0.44) | TSHRFAAHTRPV1GMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100564383-C | Organosilicon compound and manufacture method thereof | SUMITOMO CHEMICAL CO (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-1930174-A | Organosilicon compound and method for producing same | SUMITOMO CHEMICAL CO (JP) | 2007-03-14 | — | — | CN | disclosed |