Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740676 | 0.93 | DPP4 (0.41) | DPP4CCR2LIPENAMPTDPP8 | |
| SCHEMBL27664868 | 0.91 | DPP4 (0.44) | DPP4ACACBACACADPP8DPP9 | |
| SCHEMBL27643669 | 0.88 | DPP4 (0.39) | DPP4NAMPTDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL27644405 | 0.88 | DPP4 (0.48) | DPP4DPP8DPP9 | |
| SCHEMBL27664912 | 0.86 | DPP4 (0.40) | DPP4LIPEDPP9 | |
| SCHEMBL27664907 | 0.86 | DPP4 (0.42) | DPP4ACACBACACADPP8DPP9 | |
| SCHEMBL5462671 | 0.84 | DPP4 (0.43) | DPP4LIPEDPP8DPP9KDM4E | |
| Hydrochloric Acid SCHEMBL5446161 | 0.82 | DPP4 (0.54) | DPP4DPP8DPP9 | |
| SCHEMBL28758192 | 0.82 | DPP4 (0.46) | DPP4DPP8DPP9KDM4EMAPT | |
| SCHEMBL5456427 | 0.82 | DPP4 (0.42) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886376-A | Pyridine compounds as dipeptidyl dipeptidase-IV inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-12-27 | — | — | CN | disclosed |