Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 15/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 15/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665985 | 0.82 | PDE3B (0.50) | PDE3BPDE3APDE10ANEK2PLK1 | |
| SCHEMBL2090870 | 0.81 | PDE3B (0.46) | PDE3BPDE3APDE10ANEK2PLK1 | |
| SCHEMBL2090873 | 0.80 | PDE3B (0.46) | PDE3BPDE3APDE10ANEK2PLK1 | |
| SCHEMBL27666002 | 0.71 | PDE3B (0.52) | PDE3BPDE3APDE10ANEK2PLK1 | |
| SCHEMBL27665828 | 0.67 | TP53 (0.38) | — | |
| SCHEMBL2089308 | 0.67 | PDE3B (0.53) | PDE3BPDE3APDE10A | |
| SCHEMBL2089310 | 0.67 | PDE3B (0.53) | PDE3BPDE3APDE10A | |
| SCHEMBL5542091 | 0.67 | CA12 (0.44) | PDE3BPDE3APDE10A | |
| SCHEMBL2090153 | 0.66 | ACACB (0.37) | ACACB | |
| SCHEMBL2090155 | 0.65 | ACACB (0.37) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |