Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16552487 | 0.98 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL11630312 | 0.89 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL16559322 | 0.89 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL16559382 | 0.88 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL16552498 | 0.86 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL11633746 | 0.85 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL11636727 | 0.83 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL16552462 | 0.82 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL13567535 | 0.81 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 | |
| SCHEMBL11389508 | 0.81 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878546-A | Combination comprising an alpha-2 delta ligand and an SSRI and/or SNRI for the treatment of depression and anxiety | WARNER LAMBERT CO (US) | 2006-12-13 | — | — | CN | disclosed |