Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.45 |
| ▸ | NPY4R | P50391 | 9/20 | 0.45 |
| ▸ | NPY1R | P25929 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL27638364 | 0.92 | ANPEP (0.52) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL28196890 | 0.91 | NPY4R (0.46) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Tyrosine SCHEMBL9294369 | 0.91 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RSLC7A5 | |
| Arginine SCHEMBL16797368 | 0.90 | NPY4R (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL25209340 | 0.90 | SLC7A5 (0.52) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL10428660 | 0.89 | ANPEP (0.47) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL10428661 | 0.89 | ANPEP (0.47) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL3485965 | 0.89 | SLC7A5 (0.54) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL27692294 | 0.88 | ANPEP (0.48) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| Arginine SCHEMBL16323075 | 0.88 | ANPEP (0.48) | ANPEPRNPEPDNPEPNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100473695-C | Transparent polycarbonate-polysiloxane copolymer blend, method for the preparation thereof, and article derived therefrom | SABIN BASE INNOVATION PLASTIC (NL) | 2009-04-01 | — | — | CN | disclosed |
| CN-1902281-A | Transparent polycarbonate-polysiloxane copolymer blend, method for the preparation thereof, and article derived therefrom | GEN ELECTRIC (US) | 2007-01-24 | — | — | CN | disclosed |