Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 12/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107890 | 1.00 | MLNR (0.61) | MLNRMGLLPRKAA2CCR1DRD2 | |
| SCHEMBL5114477 | 0.91 | MLNR (0.75) | MLNRMGLL | |
| SCHEMBL2766444 | 0.91 | MLNR (0.75) | MLNRMGLL | |
| SCHEMBL2767245 | 0.90 | MLNR (0.72) | MLNRMGLLCCR1 | |
| SCHEMBL5113329 | 0.90 | MLNR (0.72) | MLNRMGLLCCR1 | |
| SCHEMBL3563619 | 0.90 | MLNR (0.57) | MLNRMGLLPRKAA2CCR1DRD2 | |
| SCHEMBL2767809 | 0.85 | MLNR (0.56) | MLNRMGLL | |
| SCHEMBL5114320 | 0.85 | MLNR (0.74) | MLNRMGLL | |
| SCHEMBL5104278 | 0.85 | MLNR (0.56) | MLNRMGLL | |
| SCHEMBL2766641 | 0.85 | MLNR (0.74) | MLNRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |