Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 13/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 4/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874408 | 0.81 | MAPT (0.48) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3881172 | 0.79 | MAPT (0.49) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3877422 | 0.78 | MAPT (0.45) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3873857 | 0.77 | MEN1 (0.46) | WEE1POLBMAPTATMMEN1 | |
| SCHEMBL3877435 | 0.76 | MEN1 (0.45) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3878991 | 0.75 | POLB (0.47) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3878062 | 0.72 | POLB (0.43) | POLBMAPTATMKDRMAP3K11 | |
| SCHEMBL3876445 | 0.71 | MAPT (0.47) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL3880601 | 0.71 | POLB (0.44) | WEE1CHEK1POLBMAPTATM | |
| SCHEMBL24637575 | 0.70 | POLB (0.48) | WEE1POLBMAPTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |