Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 10/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 10/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28759608 | 0.99 | DHODH (0.40) | DHODHKCNJ6KCNJ5KCNJ3LMNA | |
| SCHEMBL27637170 | 0.87 | KCNJ6 (0.43) | KCNJ6KCNJ5KCNJ3LMNAPKM | |
| SCHEMBL3860022 | 0.86 | KCNJ6 (0.46) | DHODHKCNJ6KCNJ5KCNJ3LMNA | |
| SCHEMBL27637083 | 0.86 | KCNJ6 (0.42) | KCNJ6KCNJ5KCNJ3LMNAPKM | |
| SCHEMBL3975958 | 0.85 | KCNJ6 (0.46) | DHODHKCNJ6KCNJ5KCNJ3LMNA | |
| SCHEMBL27654191 | 0.84 | DHODH (0.44) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL27729504 | 0.83 | KCNJ6 (0.45) | KCNJ6KCNJ5KCNJ3LMNAPKM | |
| SCHEMBL27654247 | 0.80 | DHODH (0.47) | DHODHLMNAMEN1KMT2APKM | |
| SCHEMBL3975262 | 0.74 | MAPK14 (0.47) | DHODHLMNAGAAMEN1KMT2A | |
| SCHEMBL3979959 | 0.73 | KCNJ6 (0.46) | KCNJ6KCNJ5KCNJ3LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946715-A | Heteroarylaminopyrazole derivatives useful for the treatment of diabetes | BAYER PHARMACEUTICALS CORP (US) | 2007-04-11 | — | — | CN | claimed |