Propene

Propene

SCHEMBL27674340

C=CC.C=CC(=O)OCCCO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.65
ALDH1A1 P00352 4/20 0.65
CYP3A4 P08684 2/20 0.65
HPGD P15428 1/20 0.64
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
HSD17B10 Q99714 1/20 0.54
THRB P10828 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 3/20 0.37
ACHE P22303 5/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26117 0.94
SCHEMBL2851828 0.94 TSHR (0.74) TSHRALDH1A1CYP3A4HPGDTP53
Alcohol SCHEMBL28427960 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28524911 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28229921 0.91
Hydroxyl Radical SCHEMBL28140965 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
Phosphine SCHEMBL31268105 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
Ammonia Solution, Strong SCHEMBL28302963 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31339001 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53
Ethylene Glycol SCHEMBL28092417 0.91 TSHR (0.71) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438740-A The preparation method of antistatic silicone rubber 浙江清华柔性电子技术研究院 2019-03-08 CN disclosed
CN-108864460-A Preparation method of antistatic silicone rubber 浙江清华柔性电子技术研究院 2018-11-23 CN disclosed
CN-103524684-B There is acrylic polymer and the production method thereof of sag prevention effect JIANGSU RONGCHANG NEW MATERIAL TECHNOLOGY Co.,Ltd. (CN) 2016-01-20 CN disclosed
CN-103524684-A Acrylic resin polymer with anti-sagging effect and production method thereof JIANGSU RONGCHANG NEW MATERIAL TECHNOLOGY CO LTD 2014-01-22 CN disclosed
CN-87107676-A Binder composition, method and product 1988-08-10 CN disclosed