SCHEMBL2767484

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3552916	0.81	EPHX2 (0.39)	ALDH1A1MAP2K4EPHX2KDM4EHPGD
	SCHEMBL2769642	0.74	EPHX2 (0.45)	MAP2K4EPHX2FFAR1HTR1ADRD2
	SCHEMBL2768550	0.74	EPHX2 (0.50)	MAP2K4EPHX2USP10PIK3C3USP13
	SCHEMBL2768610	0.73	EPHX2 (0.43)	MAP2K4EPHX2DRD2USP10PIK3C3
	SCHEMBL2768709	0.72	MEN1 (0.50)	ALDH1A1SMN1; SMN2EPHX2KDM4EFFAR1
	SCHEMBL2767372	0.72	EPHX2 (0.51)	MAP2K4EPHX2DRD2HTR2AUSP10
	SCHEMBL2768581	0.71	MAPT (0.55)	ALDH1A1SMN1; SMN2MAP2K4EPHX2KDM4E
	SCHEMBL2769470	0.71	EPHX2 (0.43)	SMN1; SMN2MAP2K4EPHX2LMNACHRNA7
	SCHEMBL2768789	0.69	EPHX2 (0.40)	ALDH1A1SMN1; SMN2EPHX2KDM4EHPGD
	SCHEMBL2768706	0.69	EPHX2 (0.46)	MAP2K4EPHX2USP10PIK3C3USP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.