Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 16/20 | 0.77 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13404778 | 0.91 | MLNR (0.72) | MLNRCCR5HPGDSSTAT3 | |
| SCHEMBL2766772 | 0.90 | MLNR (0.75) | MLNRCCR5HPGDSSTAT3 | |
| SCHEMBL2767806 | 0.87 | MLNR (0.75) | MLNR | |
| SCHEMBL2766326 | 0.87 | MLNR (1.00) | MLNR | |
| SCHEMBL2767300 | 0.83 | MLNR (0.76) | MLNRCCR5 | |
| SCHEMBL13404776 | 0.82 | MLNR (0.70) | MLNRCCR5HPGDSSTAT3 | |
| SCHEMBL3564356 | 0.82 | MLNR (0.65) | MLNRHPGDSSTAT3WNT3A | |
| SCHEMBL2767730 | 0.81 | MLNR (0.61) | MLNRHPGDSWNT3A | |
| SCHEMBL2766023 | 0.81 | MLNR (0.76) | MLNRHPGDS | |
| SCHEMBL2767231 | 0.79 | MLNR (0.76) | MLNRHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |