Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 18/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802496 | 0.86 | MLNR (0.62) | MLNR | |
| SCHEMBL2766677 | 0.86 | MLNR (0.48) | MLNRMCHR1 | |
| SCHEMBL2766964 | 0.82 | MLNR (0.41) | MLNRMCHR1 | |
| SCHEMBL4134228 | 0.81 | MLNR (0.59) | MLNRMCHR1 | |
| SCHEMBL3570120 | 0.80 | MLNR (0.53) | MLNR | |
| SCHEMBL3562286 | 0.79 | MLNR (0.58) | MLNR | |
| SCHEMBL3559461 | 0.79 | MLNR (0.60) | MLNR | |
| SCHEMBL3564356 | 0.76 | MLNR (0.65) | MLNR | |
| SCHEMBL2767430 | 0.76 | MCHR1 (0.42) | MLNRMCHR1 | |
| SCHEMBL377588 | 0.76 | CHRM4 (0.45) | MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041093-B1 | PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES | GLAXO GROUP LTD (GB) | 2010-04-21 | — | — | EP | disclosed |