SCHEMBL2767607

SCHEMBL2767607

Cc1cc(-c2ccc(C(=O)N(C)c3ccc(CN4CCN(C(=O)O)[C@@H](C)C4)cc3)cn2)ccn1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MLNR O43193 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3558322 1.00 MLNR (0.56) MLNR
SCHEMBL13404792 0.89 MLNR (0.52) MLNR
SCHEMBL2767806 0.86 MLNR (0.75) MLNR
SCHEMBL2765987 0.86 MLNR (0.73) MLNR
SCHEMBL2767564 0.86 MLNR (0.73) MLNR
SCHEMBL2767512 0.85 MLNR (0.75) MLNR
SCHEMBL2767809 0.85 MLNR (0.56) MLNR
SCHEMBL5104278 0.85 MLNR (0.56) MLNR
SCHEMBL2765775 0.84 MLNR (0.77) MLNR
SCHEMBL2767210 0.83 MLNR (0.51) MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041093-B1 PIPERAZINYL DERIVATIVES USEFUL IN THE TREATMENT OF GPR38 RECEPTOR MEDIATED DISEASES GLAXO GROUP LTD (GB) 2010-04-21 EP disclosed