SCHEMBL2767665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2769294	0.89	EGFR (0.46)	EPHX2KCNA5ALDH1A1KDM4EKAT6A
	SCHEMBL3563879	0.88	EPHX2 (0.47)	EPHX2ALDH1A1KDM4EKAT6AMAPK1
	SCHEMBL2767350	0.77	KDM4E (0.48)	ALDH1A1KDM4EKAT6AMAPK1LMNA
	SCHEMBL4933048	0.77	HIF1A (0.41)	ALDH1A1KDM4EMAPK1TSHRMAPT
	SCHEMBL2768384	0.75	KCNA5 (0.53)	KCNA5KDM4EMAPK1LMNAKMT2A
	SCHEMBL2767208	0.74	EPHX2 (0.51)	EPHX2KCNA5TP53SMN1; SMN2KMT2A
	SCHEMBL4928663	0.73	MAPT (0.45)	ALDH1A1KDM4EMAPK1TSHRMAPT
	SCHEMBL4934925	0.72	MAPT (0.41)	ALDH1A1KDM4EKAT6AMAPK1MAPT
	SCHEMBL2767262	0.71	KCNA5 (0.42)	KCNA5ALDH1A1KDM4EMAPK1TSHR
	SCHEMBL2769062	0.71	EPHX2 (0.68)	EPHX2KCNA5ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.