Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677402 | 0.98 | BRD4 (0.40) | BRD4TRPM8SIRT5MAPTL3MBTL1 | |
| SCHEMBL1486464 | 0.88 | MEN1 (0.42) | BRD4SIRT5MAPTMAOBMEN1 | |
| SCHEMBL1486461 | 0.88 | MEN1 (0.42) | BRD4SIRT5MAPTMAOBMEN1 | |
| SCHEMBL4394795 | 0.88 | BCL2 (0.46) | BRD4MAPTL3MBTL1 | |
| SCHEMBL1231815 | 0.86 | MAPT (0.42) | BRD4SIRT5MAPTMAOBMEN1 | |
| SCHEMBL1231816 | 0.86 | MAPT (0.42) | BRD4SIRT5MAPTMAOBMEN1 | |
| SCHEMBL1231851 | 0.86 | BCL2 (0.46) | BRD4SIRT5MAPTL3MBTL1 | |
| SCHEMBL1231886 | 0.83 | MAPT (0.43) | MAPTMAOBNMT1MEN1KMT2A | |
| SCHEMBL1231888 | 0.83 | MAPT (0.43) | MAPTMAOBNMT1MEN1KMT2A | |
| SCHEMBL1233933 | 0.83 | BCL2 (0.44) | MAPTNMT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1897948-A | Alkoxy substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2007-01-17 | — | — | CN | disclosed |