Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763451 | 0.79 | HRH3 (0.52) | HRH3MEN1KMT2A | |
| SCHEMBL3382029 | 0.76 | HRH3 (0.62) | HRH3MEN1KMT2A | |
| SCHEMBL3383348 | 0.75 | HRH3 (0.72) | HRH3MEN1KMT2A | |
| SCHEMBL3386166 | 0.71 | HRH3 (1.00) | HRH3MEN1KMT2A | |
| SCHEMBL4879309 | 0.70 | HRH3 (0.61) | HRH3MEN1KMT2A | |
| SCHEMBL3383267 | 0.70 | HRH3 (0.61) | HRH3MEN1KMT2A | |
| SCHEMBL3386840 | 0.69 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3382379 | 0.69 | HRH3 (1.00) | HRH3MEN1KMT2A | |
| SCHEMBL23742714 | 0.66 | CYP2D6 (0.57) | HRH3 | |
| SCHEMBL25192980 | 0.65 | HRH3 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960981-A | As histamine H3Non-imidazole heterocyclic compounds as receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2007-05-09 | — | — | CN | disclosed |