Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | MPL | P40238 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15851419 | 0.88 | CYP1A2 (0.46) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL11528715 | 0.88 | AURKA (0.49) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL28398044 | 0.87 | CYP1A2 (0.44) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL11528724 | 0.84 | AURKA (0.40) | AURKAAURKBTTRCYP1A2ATIC | |
| SCHEMBL303533 | 0.84 | CYP1A2 (0.53) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL139959 | 0.80 | AURKA (0.50) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL29825144 | 0.80 | AURKA (0.50) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL28203347 | 0.80 | AURKA (0.50) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL29623330 | 0.80 | AURKA (0.50) | AURKAAURKBTTRCYP1A2ERBB2 | |
| SCHEMBL30218795 | 0.80 | AURKA (0.42) | AURKAAURKBTTRCYP1A2ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101795662-B | UV filter capsule | MERCK PATENT GMBH | 2013-01-02 | — | — | CN | disclosed |
| CN-101795662-A | UV filter capsule | MERCK PATENT GMBH | 2010-08-04 | — | — | CN | disclosed |
| CN-101610792-A | Keratin-binding effector molecules and methods for producing same by coupling keratin-binding polypeptides to effector molecules carrying carboxyl or sulfonic acid groups | BASF AG (DE) | 2009-12-23 | — | — | CN | disclosed |
| CN-101370822-A | Keratin binding effector molecules comprising reactive dyes | BASF SE (DE) | 2009-02-18 | — | — | CN | disclosed |
| CN-101365493-A | Keratin-binding effector molecules, and method for the production thereof | BASF AG (DE) | 2009-02-11 | — | — | CN | disclosed |
| CN-101010119-A | Composition containing a dihydroxyacetone precursor | MERCK PATENT GMBH (DE) | 2007-08-01 | — | — | CN | disclosed |