Methylamine

Methylamine

SCHEMBL27679239

CCCCc1ccccc1NC(=O)c1cn(C)nc1C(Cl)Cl.CN.CN.CN

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
SLC16A3 O15427 7/20 0.42
DHODH Q02127 2/20 0.41
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
NR4A1 P22736 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ESR2 Q92731 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
DCTPP1 Q9H773 1/20 0.39
CNR2 P34972 2/20 0.38
CNR1 P21554 1/20 0.38
NR3C1 P04150 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10279909 0.82 ATM (0.48) ATMSLC16A3DHODHKDM4EPOLB
Methylamine SCHEMBL27546410 0.76 SLC16A3 (0.69) SLC16A3KDM4EPOLBRAB9ADCTPP1
SCHEMBL6013470 0.74 ATM (0.43) ATMDHODHPOLB
Methylamine SCHEMBL27546412 0.74 SLC16A3 (0.53) SLC16A3POLBTDP1
SCHEMBL13314290 0.74 IRAK4 (0.41) ATMSLC16A3
SCHEMBL3255460 0.74 ATM (0.45) ATMDHODHPOLBRAB9ASMN1; SMN2
Methylamine SCHEMBL27566515 0.73 SMN1; SMN2 (0.52) SLC16A3RAB9ATDP1SMN1; SMN2
SCHEMBL30753925 0.73 ATM (0.44) ATMSLC16A3DHODH
Methylamine SCHEMBL27679238 0.73 TP53 (0.44) SLC16A3DHODHPOLBRAB9ANR3C1
SCHEMBL169389 0.73 ATM (0.44) ATMSLC16A3DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1871219-B Hexylcarboxanilide BAYER CROPSCIENCE AG 2010-05-05 CN disclosed
CN-1871219-A Hexylcarboxanilide BAYER CROPSCIENCE AG (DE) 2006-11-29 CN disclosed