Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10259053 | 0.91 | FFAR1 (0.48) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL14350639 | 0.89 | FFAR1 (0.45) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL3283791 | 0.89 | TSHR (0.46) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL3283751 | 0.85 | TSHR (0.46) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL14350771 | 0.84 | TSHR (0.54) | TSHRLMNAALDH1A1RECQLKMT2A | |
| SCHEMBL14350638 | 0.82 | TSHR (0.52) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL14350765 | 0.82 | TSHR (0.52) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL3282766 | 0.82 | TSHR (0.42) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL27659346 | 0.81 | TSHR (0.44) | TSHRFFAR1CPT2TDP1LMNA | |
| SCHEMBL8742572 | 0.78 | TSHR (0.34) | TSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1962596-A | Ketone compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS INC (US) | 2007-05-16 | — | — | CN | disclosed |