Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL1685692 | 1.00 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1685677 | 1.00 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL27215525 | 1.00 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL3193775 | 1.00 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL76726 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9133211 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL28149900 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL18141011 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1685661 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL76960 | 0.95 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101279490-B | Method for manufacturing thermoplastic resin film, and optical compensation film and polarization plate for liquid crystal display panel | FUJI PHOTO FILM CO LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-101489758-B | Cellulose acylate film, saturated norbornene resin film, and process for producing these | FUJI PHOTO FILM CO LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-101370638-B | Thermoplastic resin film and method for producing same | FUJI PHOTO FILM CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-101184601-B | Method for producing thermoplastic film | FUJI PHOTO FILM CO LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-1997507-B | Thermoplastic film and its manufacturing method | FUJI PHOTO FILM CO LTD | 2012-06-06 | — | — | CN | disclosed |
| CN-101184600-B | Method for preparing thermoplastic film and optical compensation film for liquid crystal display panel prepared by the method | FUJI PHOTO FILM CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-101472725-B | Cellulosic resin film and process for producing the same | FUJI PHOTO FILM CO LTD | 2011-09-28 | — | — | CN | disclosed |
| CN-101272895-B | Thermoplastic resin film and method for producing the same | FUJI PHOTO FILM CO LTD | 2011-06-22 | — | — | CN | disclosed |
| CN-101258015-B | Cellulose resin film and method for producing same | FUJI PHOTO FILM CO LTD | 2011-05-25 | — | — | CN | disclosed |
| CN-101189115-B | Method for producing cellulose acylate film, and cellulose acylate film using the same, and optical compensation film for liquid crystal display plate | FUJI PHOTO FILM CO LTD | 2011-05-25 | — | — | CN | disclosed |
| CN-101258015-A | Cellulose resin film and method for producing same | FUJIFILM CORP (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101193739-A | Method for producing cellulose acylate resin film | FUJI PHOTO FILM CO LTD (JP) | 2008-06-04 | — | — | CN | disclosed |
| CN-101189115-A | Method for producing cellulose acylate film, and cellulose acylate film using the same, and optical compensation film for liquid crystal display plate | FUJI PHOTO FILM CO LTD (JP) | 2008-05-28 | — | — | CN | disclosed |
| CN-101184601-A | Method for producing thermoplastic film | FUJI PHOTO FILM CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-101184600-A | Method for preparing thermoplastic film and optical compensation film for liquid crystal display panel prepared by the method | FUJI PHOTO FILM CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-101184598-A | Method and apparatus for manufacturing cellulose acylate film and cellulose acylate film | FUJIFILM HOLDINGS CORP (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-101184599-A | Method for producing cellulose acylate film and optical compensation film for liquid crystal display plate produced by using the method | FUJI PHOTO FILM CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-101180173-A | Method for producing thermoplastic film | FUJI PHOTO FILM CO LTD (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-101027175-A | Cellulose acylate film, its manufacturing method, drawn cellulose acylate film and its manufacturing method | FUJI PHOTO FILM CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |
| CN-1997507-A | Thermoplastic film and its manufacturing method | FUJI PHOTO FILM CO LTD (JP) | 2007-07-11 | — | — | CN | disclosed |