SCHEMBL2768004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2768870	0.83	GSR (0.56)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2768161	0.82	KDR (0.50)	MAPK8MAPK9MAPK10KDM4EHSD17B10
	SCHEMBL2771305	0.81	MAPK8 (0.57)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2769418	0.80	ABL1 (0.46)	MAPK8MAPK9MAPK10KDM4EHSD17B10
	SCHEMBL2768700	0.79	MAPK10 (0.52)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2768727	0.79	MAPK8 (0.52)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2769394	0.78	MAPK10 (0.76)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2769382	0.77	NPC1 (0.44)	MAPK8MAPK9MAPK10GSRKDM4E
	SCHEMBL2771632	0.77	MAPK8 (0.44)	MAPK8MAPK9MAPK10KDM4EHSD17B10
	SCHEMBL2768451	0.77	NPSR1 (0.47)	MAPK8KDM4EHSD17B10ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.