Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966003 | 0.85 | MAOB (0.62) | PKMMAOBMAOASCN9ANR4A2 | |
| SCHEMBL2185997 | 0.85 | MAOB (0.76) | MAOBMAOASCN9A | |
| SCHEMBL31060850 | 0.85 | MAOB (0.76) | MAOBMAOASCN9A | |
| SCHEMBL2018555 | 0.85 | MAOB (0.76) | MAOBMAOASCN9A | |
| SCHEMBL964395 | 0.85 | MAOB (0.76) | MAOBMAOASCN9A | |
| SCHEMBL69031 | 0.83 | MAOB (0.60) | MAOBMAOASCN9A | |
| SCHEMBL2167382 | 0.82 | MAOB (0.71) | MAOBMAOASCN9A | |
| SCHEMBL2167372 | 0.82 | MAOB (0.71) | MAOBMAOASCN9A | |
| Isopropylamine SCHEMBL9628060 | 0.80 | MAOB (0.65) | PKMMAOBMAOARXRARXRB | |
| SCHEMBL1070558 | 0.80 | MAOB (0.56) | MAOBMAOASCN9ARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100584323-C | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders | NEWRON PHARM SPA | 2010-01-27 | — | — | CN | disclosed |
| CN-1956714-A | Alpha-aminoamide derivatives for the treatment of lower urinary tract disorders | NEWRON PHARM SPA (IT) | 2007-05-02 | — | — | CN | disclosed |