Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 15/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | DKK1 | O94907 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | CHUK | O15111 | 1/20 | 0.55 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3522035 | 0.81 | IKBKB (0.68) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3518099 | 0.78 | IKBKB (0.64) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3519764 | 0.77 | IKBKB (0.97) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3520622 | 0.76 | IKBKB (0.79) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3516622 | 0.76 | IKBKB (1.00) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3518049 | 0.76 | IKBKB (0.79) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3519410 | 0.76 | IKBKB (0.79) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3519939 | 0.76 | IKBKB (1.00) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3520628 | 0.76 | IKBKB (0.74) | IKBKBMAPK8MAPK10JAK2DKK1 | |
| SCHEMBL3518043 | 0.76 | IKBKB (0.74) | IKBKBMAPK8MAPK10JAK2DKK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039919-A | N-benzenesulfonyl substituted anilino-pyrimidine analogs | WYETH CORP (US) | 2007-09-19 | — | — | CN | claimed |
| CN-101039919-A | N-benzenesulfonyl substituted anilino-pyrimidine analogs | WYETH CORP (US) | 2007-09-19 | — | — | CN | disclosed |