Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 3/20 | 0.53 |
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20714775 | 0.83 | BLM (0.51) | LAP3ANPEPSRCPTGS1PTGS2 | |
| SCHEMBL23501799 | 0.81 | CYP2C19 (0.64) | LAP3ANPEPSRCALDH1A1CYP2C19 | |
| SCHEMBL570430 | 0.80 | ANPEP (0.41) | LAP3ANPEPPTGS1PTGS2LMNA | |
| SCHEMBL1791289 | 0.79 | TSHR (0.52) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL22579132 | 0.79 | SRC (0.48) | SRCALDH1A1PLAUCYP2C19SMN1; SMN2 | |
| 3-Methylbutanol SCHEMBL15201181 | 0.79 | ANPEP (0.53) | LAP3ANPEPSRCALDH1A1CYP2C9 | |
| Benzene SCHEMBL11142811 | 0.78 | SRC (0.73) | LAP3ANPEPSRCALDH1A1CYP2C9 | |
| SCHEMBL27676341 | 0.78 | SRC (0.73) | LAP3ANPEPSRCALDH1A1CYP2C9 | |
| SCHEMBL37038 | 0.78 | SRC (0.73) | LAP3ANPEPSRCALDH1A1CYP2C9 | |
| SCHEMBL27938230 | 0.78 | SRC (0.52) | LAP3ANPEPSRCALDH1A1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104531078-A | Compositions and methods for reducing fire hazard of flammable refrigerants | DU PONT | 2015-04-22 | — | — | CN | disclosed |
| CN-1878849-B | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT | 2014-12-24 | — | — | CN | disclosed |
| CN-1878849-A | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT (US) | 2006-12-13 | — | — | CN | disclosed |