SCHEMBL27680641

SCHEMBL27680641

C[C@H](CC=N)c1cc[c]cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680635 1.00 TAAR1 (0.30) TAAR1
SCHEMBL27416795 1.00 TAAR1 (0.30) TAAR1
SCHEMBL27889453 0.79 TAAR1 (0.30) TAAR1
SCHEMBL25392233 0.78 TAAR1 (0.52) TAAR1
SCHEMBL27747662 0.77 TAAR1 (0.31) TAAR1
SCHEMBL28776716 0.77 TAAR1 (0.31) TAAR1
SCHEMBL27747670 0.77 TAAR1 (0.31) TAAR1
SCHEMBL23983 0.76 AOC3 (0.34) TAAR1
SCHEMBL1028273 0.76 AOC3 (0.34) TAAR1
SCHEMBL1029392 0.76 AOC3 (0.34) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101421264-A Is suitable for treating serotonin 5HT6Heterocyclic compounds for receptor-modulated responsive disorders ABBOTT GMBH & CO KG (DE) 2009-04-29 CN disclosed
CN-101421243-A Aryloxyethylamine compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor ABBOTT GMBH & CO KG (DE) 2009-04-29 CN disclosed
CN-101068801-A Arylsulfonylmethyl or arylsulfonamide substituted aromatic compounds suitable for the treatment of disorders which respond to modulation of the dopamine D3 receptor ABBOTT GMBH & CO KG (DE) 2007-11-07 CN disclosed
CN-101039904-A Is suitable for treating dopamine D3Heterocyclic compounds for receptor-modulated responsive disorders ABBOTT GMBH & CO KG (DE) 2007-09-19 CN disclosed
CN-101039900-A 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor ABBOTT GMBH & CO KG (DE) 2007-09-19 CN disclosed