Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 20/20 | 1.00 |
| ▸ | ESR1 | P03372 | 15/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463222 | 0.88 | ESR2 (1.00) | ESR2ESR1HDAC6 | |
| SCHEMBL2399908 | 0.82 | ESR2 (0.70) | ESR2ESR1HDAC6 | |
| SCHEMBL1377599 | 0.82 | ESR2 (0.70) | ESR2ESR1HDAC6 | |
| SCHEMBL1379244 | 0.82 | ESR2 (1.00) | ESR2ESR1HDAC6 | |
| SCHEMBL5424079 | 0.78 | ESR2 (0.68) | ESR2ESR1HDAC6 | |
| SCHEMBL3930187 | 0.78 | ESR2 (1.00) | ESR2ESR1HDAC6 | |
| SCHEMBL5426383 | 0.78 | ESR2 (0.68) | ESR2ESR1HDAC6 | |
| SCHEMBL1376248 | 0.78 | ESR2 (1.00) | ESR2ESR1HDAC6 | |
| SCHEMBL1375183 | 0.78 | ESR2 (1.00) | ESR2ESR1HDAC6 | |
| SCHEMBL1375196 | 0.78 | ESR2 (1.00) | ESR2ESR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101044126-A | Prodrug substituted benzoxazoles as estrogenic agents | WYETH CORP (US) | 2007-09-26 | — | — | CN | claimed |
| CN-101044126-A | Prodrug substituted benzoxazoles as estrogenic agents | WYETH CORP (US) | 2007-09-26 | — | — | CN | disclosed |